Gamete intra-fallopian transfer, commonly known as GIFT, is a reproductive procedure where both sperm and eggs are collected from a couple and then manually inserted directly into a woman’s fallopian tubes. This assists natural fertilization to take place inside the woman’s body. It’s a form of assisted reproductive technology typically used for couples who have unexplained fertility problems or issues with the woman’s fallopian tubes.

Key Takeaways

  1. Gamete intra-fallopian transfer (GIFT) is an assisted reproductive procedure that directly places an unfertilized egg and sperm into a woman’s fallopian tubes, facilitating natural fertilization.
  2. This method requires both partners to undergo medical procedures; it’s a successful fertility treatment for couples unable to conceive due to issues with sperm mobility or unexplained infertility.
  3. Unlike In Vitro Fertilization (IVF), GIFT maintains a natural conception process within the female body and allows fertilization to happen internally.


Gamete intra-fallopian transfer, also known as GIFT, is an important term in motherhood due to its association with assisted reproductive techniques to help address infertility.

GIFT is a procedure that involves collecting a woman’s eggs, mixing them with sperm, and immediately placing them into the fallopian tubes, in hopes of initiating natural fertilization and subsequent pregnancy.

It’s known as being a method that closely mimics the natural fertilization process.

This method is critical for couples who may struggle with specific forms of infertility, offering them a potential solution to achieve pregnancy and motherhood.

Its importance therefore lies in its role in expanding the possibilities of parenthood to individuals who may not be able to achieve it otherwise.


Gamete intra-fallopian transfer (GIFT) is primarily used as a fertility treatment for couples who have experienced difficulty conceiving naturally. This treatment is particularly beneficial for those suffering from issues like low sperm counts or issues with the woman’s fallopian tubes.

The purpose of GIFT is to aid in conception by placing the sperm and eggs directly into the woman’s fallopian tubes, ideally imitating the natural fertilization process as closely as possible. The primary reasons for using GIFT over alternative treatments such as in vitro fertilization (IVF) typically involve a desire for a more natural form of conception or for specific religious or moral reasons.

GIFT allows fertilization to occur within the body rather than in a laboratory which may appeal to couples seeking a less ‘medicalized’ experience of conception. However, it’s important to note that a functional fallopian tube(s) is necessary for GIFT to have success, which may not necessarily be the case for all couples seeking fertility support.

Hence, professional advice from healthcare experts is essential to decide the most suitable treatment on a case-to-case basis.

Examples of Gamete intra-fallopian transfer

A couple with unexplained infertility, who have not seen success with other types of fertility treatments like in-vitro fertilization (IVF), choose to undergo gamete intra-fallopian transfer (GIFT). In this real-world scenario, the woman’s eggs and her partner’s sperm are collected, then a laparoscopic procedure is used to place both the sperm and eggs directly into her fallopian tubes, allowing fertilization and implantation to occur naturally.

A woman has a male partner with low sperm count or motility. They’ve tried intrauterine insemination (IUI) and IVF but neither have worked. Their doctor recommends GIFT, because it allows a larger number of sperm to be placed directly into the fallopian tubes, increasing the chance of fertilization.

A woman is diagnosed with ovulatory disorders that are making it difficult to conceive naturally. They decide to try GIFT because the procedure doesn’t require the woman’s body to fertilize the egg and embryo in the same way IVF does. Rather, the sperm and eggs are placed into the fallopian tube, leaving the rest to the body’s natural processes. This may improve their chances of a successful pregnancy.

Frequently Asked Questions about Gamete Intra-fallopian Transfer

What is Gamete Intra-fallopian Transfer (GIFT)?

Gamete Intra-fallopian Transfer, commonly known as GIFT, is a type of Assisted Reproductive Technology (ART) that helps with fertilization. In GIFT, an egg and sperm are placed directly into a woman’s fallopian tubes to encourage natural fertilization.

How does the GIFT procedure work?

In the GIFT procedure, both eggs and sperm are collected from the couple. Mixed eggs and sperm are then transferred to the woman’s fallopian tubes through a minor surgical procedure. The fertilization then happens naturally inside the woman’s body.

Who can benefit from GIFT?

GIFT is beneficial for couples who have unexplained fertility issues or women with at least one functioning fallopian tube. Since GIFT allows fertilization to take place inside the woman’s body, it’s also a preferred option for couples with certain ethical or religious beliefs.

What are the success rates of GIFT?

Success rates of GIFT vary depending on many factors, such as age, fertility issues, and overall health. Clinically, GIFT has shown similar success rates as In-Vitro Fertilization (IVF). However, it’s important to discuss with a fertility expert to understand the odds better.

What risks are associated with GIFT?

Like other fertility treatments, GIFT carries a risk of multiple pregnancies. There’s also a slight risk of infection or injury during the procedure. After the surgery, the woman might feel minor discomfort or pain. In rare cases, there’s a chance for ectopic pregnancy as well.

Related Motherhood Terms

  • In Vitro Fertilization (IVF)
  • Zygote Intra-fallopian Transfer (ZIFT)
  • Assisted Reproductive Technology (ART)
  • Fallopian Tubes
  • Embryo Transfer

Sources for More Information

  • Mayo Clinic: A trusted source for health-related information.
  • WebMD: A source which provides valuable health information, tools for managing your health, and support to those who seek information.
  • Medical News Today: A leading source for the latest headlines on health and medical news.
  • Healthline: Healthline provides objective, trustworthy, and accurate health information to its users in a clear and comprehensible way.