Chorioamnionitis is a bacterial infection that inflames the membranes surrounding the fetus, specifically, the chorion and the amnion. It often occurs when bacteria ascend from the vagina into the uterus. This condition can cause serious complications during pregnancy such as preterm labor, infections in the newborn, and, in rare cases, maternal bacteremia.

Key Takeaways

  1. Chorioamnionitis, also known as intra-amniotic infection (IAI), is a bacterial infection that can occur during pregnancy. It affects the membranes surrounding the fetus (the amniotic sac) and the amniotic fluid.
  2. This condition can cause severe problems if not promptly treated. It can lead to serious infections in both the mother and the baby, premature birth, and in rare cases, can be life-threatening.
  3. The main symptoms of Chorioamnionitis may include a fever, increased heart rate (both mother and baby), uterine tenderness, a foul smell from the vaginal discharge, and the presence of maternal leukocytosis. However, it can also be asymptomatic, becoming apparent only after complications arise.


Chorioamnionitis, also known as intra-amniotic infection (IAI), is a vital term in motherhood as it is a condition that can present potential health challenges during pregnancy.

It is an inflammation or infection in the membranes that surround the fetus (chorion and amnion) and the amniotic fluid.

Most commonly caused by bacteria ascending from the vagina into the uterus, chorioamnionitis can result in serious complications such as preterm birth, infections in the newborn, or even stillbirth.

Therefore, it represents a significant Maternal-Fetal medicine concern that requires timely detection and effective management to ensure the health and safety of both the mother and the baby during the prenatal and perinatal period.

The term’s importance lies in its role in dictating treatment approaches and improving pregnancy outcomes.


Chorioamnionitis, also known as intra-amniotic infection, is a condition that can affect pregnant mothers. While it may not be termed ‘for use’ in the conventional sense, the detection and management of this condition is vital in ensuring the health and safe delivery of the baby, and the well-being of the mother. Essentially, chorioamnionitis is an inflammatory condition that affects the fetal membranes (the chorion and amnion) due to a bacterial infection.

It can be caused by natural, vaginal flora bacteria or ruptured membranes allowing external bacteria into the womb, both potentially endangering the health of mother and child. Understanding and managing chorioamnionitis is crucial as it can lead to serious complications such as sepsis, preterm birth or even neonatal death if left unchecked. The mother can also experience postpartum complications like endometritis or pelvic abscess.

Thus, the ‘purpose’ of chorioamnionitis in the context of motherhood is its role as a potential risk to be closely monitored for during pregnancy and labor. Preventive measures, early detection, and immediate treatment, including the use of antibiotics, can protect mother and baby from potentially life-threatening complications. Hence, awareness of chorioamnionitis is important to the health and successful delivery of the child.

Examples of Chorioamnionitis

A maternal patient in a hospital: A pregnant woman gives birth at a hospital and, during her labor, her body temperature spikes. There are concerns that she has contracted chorioamnionitis, an inflammation of the fetal membranes. She is immediately given antibiotics and doctors monitor her baby after birth for any signs of infection. In this case, both the mother’s and the infant’s health could be affected.

A prenatal check-up scenario: A pregnant woman went for her regular prenatal check-up. She has been experiencing high fever and severe abdominal pain, which could indicate the possibility of chorioamnionitis. Her OB/GYN advised her to hospitalize immediately for antibiotic treatment to prevent harm to her unborn baby.

A childbirth preparation class: An instructor discusses different complications that can arise during labor, one of which is chorioamnionitis. The participants learn about the potential causes and symptoms, as well as the steps medical professionals take to treat this condition and ensure both mother and baby’s health.

Frequently Asked Questions about Chorioamnionitis

What is Chorioamnionitis?

Chorioamnionitis, also known as intra-amniotic infection (IAI), is an inflammation of the fetal membranes due to a bacterial infection. It typically results from bacteria ascending into the uterus from the vagina and is most often associated with prolonged labor.

What are the symptoms of Chorioamnionitis?

Symptoms may include fever, abdominal pain, foul-smelling vaginal discharge, and fast heart rate in both the mother and the fetus. However, in some cases, there might not be any visible symptoms.

Who is at risk for Chorioamnionitis?

Women with ruptured membranes, long labor, or multiple vaginal exams during labor are more at risk. Other factors could be having a weak immune system, being of a young age, or having a bacterial infection.

How is Chorioamnionitis diagnosed?

Doctors can diagnose Chorioamnionitis based on physical signs and symptoms, but lab tests of amniotic fluid may be necessary for confirmed diagnosis.

What are the treatment options for Chorioamnionitis?

Chorioamnionitis generally requires antibiotics and, in some cases, inducing labor or Cesarean delivery to prevent further complications. It’s crucial to maintain open communication with healthcare providers to discuss all available treatment options.

What are potential complications from Chorioamnionitis?

Untreated Chorioamnionitis can lead to serious complications like blood clotting, heavy postpartum bleeding, or transmission of the infection to the newborn. It can sometimes also lead to preterm birth.

Can Chorioamnionitis be prevented?

While it is not always possible to prevent Chorioamnionitis, some strategies like regular prenatal care, prompt treatment of any bacterial infections during pregnancy, and limiting the number of vaginal exams during labor may help reduce the risk.

Related Motherhood Terms

  • Intrauterine Infection
  • Maternal Fever
  • Neonatal Sepsis
  • Prolonged Labor
  • Preterm Birth

Sources for More Information

  • Mayo Clinic: They provide a comprehensive library of medical conditions and diseases, including Chorioamnionitis.
  • Cedars Sinai: Cedars-Sinai is among the leading healthcare providers in the United States well-versed in providing information on various medical topics.
  • Healthline: Healthline is an online resource dedicated to offering objective, trustworthy, and accurate health information.
  • WebMD: WebMD provides valuable health information and tools for managing health, and support to those who seek information.