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How safe is Tamiflu for your kids? The treatment has its own risks and benefits

This year’s flu season is already the worst North America has endured in a decade—which is, of course, a concern for parents of young children, who are more likely to experience serious complications from the illness.


If you or your children are struck by the flu, your health care provider is likely to write up a prescription for Tamiflu: If taken within 48 hours of symptom appearance, the antiviral drug may lessen the duration and severity of the flu. This application is recommended by both the American Academy of Pediatrics and the Centers for Disease Control and Prevention for use in infants as young as 2 weeks old.

It is also approved for preventative treatment, meaning it may help other members in the household avoid the flu if a member of the family has already been diagnosed with the illness.

For parents of young children or those at higher risk for flu complications, this makes Tamiflu a particularly good option, says Allan Greissman, MD, a pediatric critical care specialist at Pediatric Critical Care of South Florida.

“Unfortunately this year we are seeing a large number of flu-positive pediatric patients having a very serious strain of the flu. We are also seeing many more deaths from the flu and many kids with other significant problems related to the flu,” Greissman tells Motherly. “So for that reason, getting a flu shot and treatment with Tamiflu should strongly be considered.”

As with any medication, individuals should weigh the potential benefits versus risks.

“For a very mild case, especially after the first 24 to 48 hours, then taking Tamiflu may not be worth the risk of the side effects,” Greissman says. “But I want to stress that the side effects are not common and typically not serious.”

As Greissman notes, it’s always best to consult with your own doctor or child’s pediatrician. To help guide your questions, here’s a primer for what parents should keep in mind about Tamiflu.

How effective is Tamiflu?

According to a 2014 report in the British Medical Journal that reviewed results from 83 clinical trials, Tamiflu was shown to alleviate symptoms an average of 17 hours earlier for adults and 29 hours earlier for otherwise healthy children.

Tamiflu also had demonstrable benefits as a preventative treatment by reducing “symptomatic influenza in participants by 55%” if the participant was in close contact with someone who already had the flu.

The key, Greissman says, is beginning course of treatment within 48 hours of flu symptom appearance. “After that, it loses its effectiveness,” he says. “So it’s hard to say that for a child sick for a few days, that then sees his doctor, whether or not starting it is indicated. While typically we say, ‘It can't hurt to try it,’ the late effect is typically not helpful.”

What are the side-effects of Tamiflu?

According to the CDC, the most common side-effects of Tamiflu are nausea and vomiting. Specifically among children, one clinical study cited by the CDC found that 14% of adolescents who took Tamiflu had vomiting compared with 8% who took a placebo.

The studies aggregated for the British Medical Journal also noted increased risks headaches and renal or psychiatric syndromes—with the researchers noting data remains limited “because of rarity of such events and problems with study design.”

About the threat of psychiatric symptoms

The latter potential side-effect—“psychiatric symptoms”—has been the most newsworthy through the years.

In 2007, there was significant backlash to the drug following reports that 12 children in Japan died after experiencing “abnormal behavior,” such as jumping from tall balconies, following use of Tamiflu during the 2005 flu season. Although the number of deaths was statistically small—with 16 million people in Japan taking Tamiflu that season—the fatalities were understandably concerning.

As a result, Tamiflu manufacturer Roche began a new series of trials. Federal investigations were also launched in Japan, the United States and Canada.

According to a Roche document released by the Food and Drug Administration, follow-up studies found no link between the use of Tamiflu and psychiatric incidents—noting instead that the behavior was more likely a side-effect of the flu. (According to experts from the Mayo Clinic, one of the leading causes of delirium among children is high fever, which is also a symptom of the flu.)

“Roche concludes from the body of all available data that, based on the temporal relationship of the neuropsychiatric adverse events both to influenza and Tamiflu, it is difficult to distinguish between drug and disease. The relative contribution of Tamiflu to the incidence or severity of the neuropsychiatric events seen in influenza patients is unknown.”

A similar conclusion was reached by the FDA:

“Review of the available information on the safety of Tamiflu in pediatric patients suggests that the increased reports of neuropsychiatric events in Japanese children are most likely related to an increased awareness of influenza-associated encephalopathy, increased access to Tamiflu in that population, and a coincident period of intensive monitoring adverse events. Based on the information available to us, we can not conclude that there is a causal relationship between Tamiflu and the reported pediatric deaths.”

Health officials in Japan still took a cautious approach by banning the prescription of Tamiflu among people aged 10 to 19 starting in 2007, although Japan’s Ministry of Health, Labor and Welfare moved toward lifting the ban in 2016. More recently, The Japan Times reported officials from the Ministry found “multiple instances of adverse events were also reported among people who had not taken flu drugs,” which suggested “a potential link between adverse events and high fever” was stronger than the potential link with Tamiflu itself.

This is all reflected in a warning on the Tamiflu label, which reads, “Patients with influenza, including those receiving Tamiflu, particularly pediatric patients, may be at an increased risk of confusion or abnormal behavior early in their illness. Monitor for signs of abnormal behavior.”

Although Greissman says he has not seen any serious side-effects to Tamiflu that would cause him to recommend cessation, he says decisions about treatment are best left to your child’s prescribing physician.

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Just because new moms aren't hitting the gym doesn't mean they aren't doing one of the most demanding workouts of all: It takes about 20 calories to produce one ounce of milk. So, with babies who down ounces upon ounces each day, that means breastfeeding mothers can easily burn hundreds of calories almost literally in their sleep.

All that hard work can result in quite an appetite, which can have new moms reaching for whatever is most convenient. But convenience doesn't have to come at the cost of good nutrition, taste and lactation-boosting powers—as proven by the delicious Booby Boons Lactation Cookies from Stork and Dove.

"Nourishing your body is just as important now as it was when you were pregnant. Not only are you recovering from pregnancy and birth, you are making milk to sustain your baby—and all the thousands of other things you do for them every single day," says Diana Spalding, Motherly's Birth Expert, midwife and pediatric nurse. "You are working so hard, mama. You deserve to fuel your body with the best—and it doesn't hurt when the best also happens to be delicious."

Here's why these little cookies are such lactation powerhouses:

Oats

The natural goodness of oats does so much more than make for tasty cookies. Considered to be a top galactagogue—or a substance that helps boost milk supply—oats are rich in iron, fiber and protein. Because low iron can reduce milk supply, mixing a scoop of oats into lactation cookies is a tasty way to give your body the boost it may need.

Nutritional yeast

For generations, nutritional yeast has been a remedy suggests to mamas looking to boost their milk supply. And for good reason: With protein, phytoestrogen and B12 found in fortified versions, nutritional yeast can provide nutrients to stimulate milk supply—while also offering a boost of energy.

Flax meal

Rich in Omega-3 fatty acids, flaxseed is good for the brain health of mothers and babies. Not to mention that with a nice nutty taste and great protein profile, they make nice additions to lactation cookies by helping you stay full longer.

Chia seeds

When it comes to lactation cookies and promoting brain development, varied sources of Omega-3 fatty acids are so helpful—and chia seeds deliver there. Found in some of the Booby Boons Lactation Cookies, chia seeds also deliver protein, calcium and magnesium.

Probiotics

Few things can take a toll on milk supply like when you're under the weather. Booby Boons+ Lactation Cookies provide a probiotic boost, keeping your immune system up and digestive health in check for better production—and a healthier-feeling mama.

Bonus: A sense of relaxation and ease is clinically proven to aid in milk production.

Even better, the cookies are wheat-, soy- and preservative-free! So grab a cookie, take a moment for yourself and boost that supply. Grab your cookies HERE or at Target and other fine retailers.

This article was sponsored by Stork and Dove. Thank you for supporting the brands that support Motherly and mamas.

When I was pregnant I worried about what would happen if the baby cried for me while I was in a deep sleep. Like so many pregnancy worries, though, blocking out my baby's cries was something I didn't really need to be concerned about. An alarm clock can go off inches from my head and I'll sleep through it for hours, but if my baby cries at the other end of the house, I'm wide awake.

It turns out, the sound of my baby crying impacts my brain very differently than a beeping alarm.

I'm hardly the first parent to make this observation, and science is on to it, too. There's plenty of research about how a baby's cries impact its mother on a physical level. A study of mother mice published in Nature found that adding oxytocin (a hormone released in strong doses during labor and lactation) to the brains of the mamas changed the way they processed the sound of crying pups—and helped them learn how to recognize and respond to the sounds.

A dose of this “motherhood hormone," it seems, leads to increased sensitivity to the sound of your child in distress.

According to Robert Froemke, that study's senior investigator, this suggests oxytocin amplifies the way the auditory cortex processes incoming cries from our own babies. He says the same seems to be true for female mice as female humans: The sound of a crying baby stirs up a great sense of urgency.

This physiological reaction allow us to develop rapid, reliable behaviors to our babies' cries, says Froemke. In time, it also helps us learn what the cries mean—and how we can respond in a helpful way.

When our babies cry, “[as parents, we] don't know what's really going to work, we just try a bunch of stuff. Let's change a diaper, let's feed the baby, let's do a little dance," he says. “Eventually we learn this repertoire of parenting skills because we're all in, we're all invested and that baby depends on us absolutely to take care of it."

Researchers believe that it may be this hormonal shift in the brain that alerts a mother to the sound of her child's cry.

Mothers' brains have a different level of sensitivity to crying babies

In humans and in mice, dads often respond to a baby's cries, but the brain chemistry is a little different: According to Froemke, extra oxytocin doesn't speed up the reaction to crying pups in male mice the way it does for females.

"There is a difference in terms of [ a father's] sensitivity to oxytocin. We think that may be because the male oxytocin system is already maxed out," he explains, adding there is something about living with a female and child that contributes to a natural oxytocin increase in mouse dads. (Further proof moms aren't the only ones to deal with big hormone changes.)

But when it comes to the brains of human parents, there is more evidence that the brains of men and women respond to crying babies differently. A study published in NeuroReport looked at the brains of 18 men and women who heard a baby crying while inside a brain scanner. The women's brain activity suggested an immediate alertness, while the men's brain activity didn't change.

That study suggests there are gender differences in the way we process baby sounds, but a lot of dads will tell you they can't and don't sleep through a baby cries. And that's for good reason: According to Froemke, it's no biological accident that babies signal distress in a way that can pierce parents brains even when our eyes are closed.

"Parents have to sleep, too," he says, but, "Sounds penetrate our brains, they tap into something deep and we can quickly rouse from a deep slumber, jump out of bed and tend to infant needs."

Just as my son is biologically wired to be my personal alarm clock, I am biologically wired to hear him—even if I can still sleep through everything else.

[Originally published October 18. 2017]

Baking Christmas cookies together is a family tradition for many, but the Centers for Disease Control is warning parents that if your recipe contains raw flour or raw eggs, you really shouldn't sneak a bite before it is cooked, and neither should your kids.

The CDC is warning people not to eat raw cookie dough, cake mix or bread as we head into prime baking season.

The agency acknowledges the appeal of a spoonful of chocolate chip goodness but asks that we "steer clear of this temptation—eating or tasting unbaked products that are intended to be cooked, such as dough or batter, can make you sick."

Salmonella from raw eggs is, of course, a concern, and so is the raw flour. According to the CDC, flour needs to be cooked in order to kill germs like E.Coli. That's why the CDC is asking parents to "say no to raw dough," not just for eating but even for playing with.

"Children can get sick from handling or eating raw dough used for crafts or play clay, too," the CDC posted on its website.

On the Food and Drug Administration's website, that agency advises that "even though there are websites devoted to 'flour crafts,' don't give your kids raw dough or baking mixes that contain flour to play with." Health Canada also states that raw flour should not be used in children's play-dough.

The warnings follow a 2016 E.coli outbreak linked to contaminated raw flour. Dozens of people got sick that year, and a post-outbreak report notes that "state investigators identified three ill children who had been exposed to raw flour at restaurants in Maryland, Virginia, and Texas. Restaurant staff had given them raw dough to play with while they waited for their food to be served."

The CDC worries that with flour's long shelf life, products recalled during the 2016 outbreak may still be in people's pantries (although the CDC notes that any raw flour—recalled or otherwise—should not be consumed).

If your kids do have flour-based play dough, don't worry.

Some parents are still choosing to use flour-based craft dough to make Christmas ornaments or other crafts this holiday season and are reducing the risks by A) making sure the kids aren't eating their art, and B) thoroughly washing little hands, work surfaces, and utensils when the dough play is over.

Other parents are choosing other types of craft clay over flour-based dough.


During the 2016 outbreak, the FDA called for Americans to abstain from raw cookie dough, an approach Slate called "unrealistic and alarmist," noting that "the vast, vast majority of people who consume or touch uncooked flour do not contract E. coli or any other infection."

Two years ago, 63 Americans were made sick by E. coli infections linked to raw flour, according to the CDC. We don't know exactly how many Americans ate a spoonful of cookie dough or played with homemade play dough that year, but we do know that more than 319 million Americans did not get sick because of raw flour.

Are there risks associated with handling and consuming raw flour? Yes, absolutely, but it's not something to panic over.

Bottom line: Don't let your kids eat raw dough when they're helping you bake cookies for Santa, and be mindful of raw flour when choosing crafts for kids.

(And if you have just got to get your raw cookie dough fix, the CDC notes that cookie dough flavored ice cream is totally safe as it "contains dough that has been treated to kill harmful bacteria." Sounds like mama's getting Ben & Jerry's tonight.)

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They're certainly in a position where they could buy every item on their kids' Christmas lists, but Mila Kunis and Ashton Kutcher aren't planning on piling up the presents under the Christmas tree this year.

"So far, our tradition is no presents for the kids," Kunis said in an interview with Entertainment Tonight. Mom to 4-year-old daughter, Wyatt, and 2-year-old son Dmitri, Kunis says she and Kutcher are determined to not raise entitled kids—and are learning from the mistakes of Christmases past.

“We've told our parents, 'We're begging you: If you have to give her something, pick one gift,'" Kunis said. “'Otherwise, we'd like to take a charitable donation, to the Children's Hospital or a pet... Whatever you want.' That's our new tradition."

The minimalist Christmas that Kunis and Kutcher embrace makes sense on a lot of levels: It teaches kids how to be more mindful consumers, removes the emphasis on material goods... And saves you from those chaotic trips to the mall.

Going without presents doesn't mean going without

Putting a halt on presents these upcoming holidays is one way to reinforce what the season is really about: Spending quality time together as families and cherishing what we already have. But "no presents" doesn't mean "no fun," either.

Some of our favorite non-material gift suggestions include:

  • Experiences
  • Lessons
  • College contributions
  • Coupon booklets
  • Piggy bank donations
  • Gifts for others

Or you could take a cue from Kunis and Kutcher without going all the way: Maybe you only focus on one or two quality gifts. Or pass on anything that will likely get discarded to the bottom of the toy box before next year's holidays.

Think of Christmas gifts for kids kind of like eggnog: A little goes a long way.

[Originally published October 11, 2017]

After feeling alone and suffering silently for years, Gabrielle Union has been very open about her struggle with infertility since her memoir, We're Going to Need More Wine, came out last year. She surprised many by writing about how she'd suffered "8 or 9 miscarriages" while trying to conceive with husband Dwyane Wade, and just over a year later the couple surprised the world again by announcing they'd just welcomed a baby girl via surrogate.

Union's story is incredible, and one so many women needed to hear, and that's why Oprah's OWN network just aired a sit-down interview special with Union and Wade: Oprah at Home with Gabrielle Union, Dwyane Wade & Their New Baby.

(The audio version of the interview drops in two parts on 'Oprah's SuperSoul Conversations' podcast on Monday, December 10, and Wednesday, December 12.)

The interview, which first aired over the weekend, saw Union open up about how the years of IVF treatments and disappointment left her questioning everything she knew. "I've just always been of the mindset — because this is what people tell you: 'You work hard, you do the right things, you're a good person, it will happen for you,' eventually," Union, 46, told Oprah.

"I could not let go of this idea of creating this life within me," Union explains, adding that she felt the "need to be pregnant for everybody, including myself."

As the medical interventions escalated, Wade became worried. "I'm watching her do things to her body and to herself that it's getting to the point where it's not healthy," he told Oprah, adding that he always told Union that he wanted a baby as much as she did, but that he married her and that she was the most important thing to him.

"So it came to a point where, you know, I started to feel a certain way about that because I didn't want something to happen to her," Wade told Oprah.

So when the couple decided to explore surrogacy, Wade was pleased to see the medical part of his wife's journey come to an end.

When the couple surprised the world by announcing the birth of their daughter, Kaavia James, Union was puzzled by comments that insinuated the skin-to-skin photo she used in the birth announcement was an attempt to "act like" she'd been pregnant herself, or that she really had been pregnant herself.

She notes she never tried to make it seem like she'd been pregnant, as she explained her daughter was born via surrogate in the caption for that photo, which was taken after the surrogate had a C-section.

"Our surrogate went into recovery, and we were able to go immediately into another hospital room," Union told Oprah. "I had one of my New York & Company sweaters on, but skin-to-skin was kind of hard. And because the doctors kept coming in…it was easier to have skin to skin in a hospital gown."

Wade said he found the comments painful. "I think for me the most hurtful thing was once we had the baby, and everyone started talking about why is she in the bed holding the baby, why does she have a gown on, why is she acting that she just had a baby," Wade said.

Union and Wade say they hope talking about their story will help others tell theirs, and know that they are not alone. "So many people are suffering in silence and every time, when we're candid and transparent about our journeys, no matter what those journeys are, you are allowing people to be seen and heard and empowered in ways that they've never been," Union told Oprah.

She may have felt alone during her journey to motherhood, but by telling her story, Union is making sure other mamas don't.

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